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"Yes". HCG is considered safe. Very low calorie diet are more likely to cause medical problems. As long as the diet is very low calories is under medical supervision, and diet HCG is safe. Medical supervision is necessary because generates very low diet with ketosis calorie and protein deprivation may occur. These conditions can cause medical problems. Secondly, existing medical conditions person that may prevent the use of diet in hCG or you may need to modify diet program.